Necroptosis: Molecular Signalling and Translational Implications

Necroptosis: Molecular Signalling and Translational Implications

Blog Article

Necroptosis is a form of programmed necrosis whose molecular players are partially shared with apoptotic cell death.Here we summarize what is known Swaybars about molecular signalling of necroptosis, particularly focusing on fine tuning of FLIP and IAP proteins in the apoptosis/necroptosis 132 balance.We also emphasize necroptosis involvement in physiological and pathological conditions, particularly in the regulation of immune homeostasis.